CircO2: The 20-Minute Miracle for Restoring Youthful Energy, Sharpness & Vitality
CircO2 is a speedily dissolving oral lozenge that safely and effectively increases the production of nitric oxide levels in the body by 200 per cent in under 20 minutes. That is a very different mechanism because traditionally, nitric oxide would be produced in the mouth and bypass the inefficiencies defined by traditional supplements. CircO2 is a complete energy support system for blood flow, brain function, and overall health, thanks to its strong mix of nitrate-rich beetroot powder, absorption-boosting hawthorn berry, high-quality L-citrulline, and essential vitamins.
The clock turns backward on energy levels, wouldn’t you love that? To return to the days of mental sharpness, physical stamina, and vibrant vitality, everything from those days goes down the drain with the passage of time, and now one wonders what one could get to capture that all over again. What if the elusive key to all that energy had to do with a simple molecule whose presence seems to be very low in your body? Groundbreaking science has discovered that an inexplicably high percentage, approximately 75%, of the critical “youth molecule” decreases by age 70, contributing to fatigue, brain fog, and poor circulation. What if it could be restored in large amounts in just 20 minutes?
Enter CircO2, the revolutionary lozenge product of an MIT discovery that turns the wellness world topsy-turvy. Forget useless pills and unrealistic diets. What this publication is about is a direct, clinically proven approach to resetting your body’s core energy and circulation system. This whole guide will comprehensively tell you how CircO2 works, why it is unlike anything else in the market, and how it can get you back on an active, engaged, and vibrant life you used to live.
Why Choose CircO2

Made in the USA
With pride, CircO2 is produced in the USA in accordance with tight manufacturing guidelines.

FDA Approved
CircO2 is made in a facility that is registered with the FDA, ensuring both quality and safety.

GMP-Certified
The Good Manufacturing Practice (GMP) standards have been met by this product's certification.

100% Natural
With CircO2, made entirely of natural substances for your health and wellbeing, you may embrace the power of nature.
What is CircO2
CircO2 – more than just a supplement, a focused nutritional technology founded on an important physiological discovery. CircO2, at its very heart, directly addresses the serious decline in Nitric Oxide, or NO—a gaseous signalling agent that’s the master regulator of your cardiovascular and circulatory systems—due to the ageing process.
Nitric oxide is the chief communication officer for blood flow in the body. This molecule signals blood vessels to relax and dilate (vasodilation), ensuring efficient delivery of oxygen and life-sustaining nutrients to every organ, muscle, and brain cell. It is critical in maintaining healthy blood pressure, powering physical stamina, sharpening mental focus, and supporting sexual health. Without this adequate supply of NO, your entire system operates on a power shortage.
This is rather a disturbing fact, according to research in CircO2, it shows the amount of nitric oxide that one’s body could generate hugely drops, 70 per cent lower by the time you reach 70 years. It is indeed a number, but a number that explains why most people age get tired, forget quite a lot of things, feel cold ends, and lose their stamina, but usually refer to them as just normal ageing.
That distinguishes CircO2 from other products, its formulation and delivery. Instead of poorly absorbed pills or impractical amounts of food, it uses a lozenge that dissolves on the tongue. This directly engages the oral bacteria responsible for the first and most crucial step in the nitrate-to-nitrite-to-nitric oxide pathway. This pathway, validated by MIT research, promotes a very quick and profound increase in NO levels, literally kick-starting one’s own circulation and energy systems in synergy with a well-chosen, evidence-based array of ingredients.
How Does CircO2 Work? The MIT Breakthrough Explained.
The journey of CircO2 begins with a pivotal discovery from the Massachusetts Institute of Technology (MIT). Scientists found that a significant portion of the body’s nitric oxide production doesn’t start in the gut with a pill, but in the mouth, specifically on the surface of the tongue.
Here’s the simple, two-step science:
1. The Oral Kickstart: Your tongue hosts beneficial bacteria that convert dietary nitrates (like those from beets) into nitrites. This is the essential first conversion in the nitric oxide pathway. Traditional capsules and tablets bypass this oral phase entirely, losing a massive opportunity for efficiency.
2. Systemic Activation: When you swallow your saliva containing these newly formed nitrites, they travel to the stomach and are further absorbed into the bloodstream. In the acidic environment of the stomach and within the blood vessels themselves, these nitrites are converted into the precious Nitric Oxide gas.
CircO2 is engineered to exploit this natural process perfectly. You simply place a pleasantly flavored lozenge on your tongue and let it dissolve. As it does, it delivers a concentrated dose of nitrates and supporting nutrients directly to the oral bacteria, kickstarting the entire production chain. Clinical testing on this method showed a 200% increase in nitric oxide levels within 20 minutes and a 34% increase in blood flow. No stomach-delivered supplement can claim this speed or efficacy.
The CircO2 Ingredient Symphony: How Each Component Works
The unique power of CircO2 comes not from a single magic bullet but from a symphony of ingredients that play a vital role in supporting and augmenting nitric oxide production and its myriad benefits.
Main Ingredients:
• Beetroot Powder: The ultimate provider of nitrate. Beetroot is nature’s richest source of dietary nitrates, which are actually the compounds your oral bacteria would use to initiate NO production. This means with a concentrated standardised dose provided by CircO2, you’ve given your body the foundational building blocks it requires, sparing you from having to eat pounds of beetroot every day.
• Hawthorn Berry: The enhancer of absorption. Used for centuries in traditional medicine for heart support, modern science shows that hawthorn berry enhances vasodilation in blood vessels. Think of it as enhancing the cardiovascular system’s “receptivity” to utilise and respond to nitric oxide in an efficient manner, further multiplying the benefit.
• L-Citrulline: The precursor deluxe. Numerous supplements employ L-arginine (which gets deactivated during digestion and gets harder to convert after 45); CircO2 employs L-citrulline. The latter is stable, converts to L-arginine in the kidneys, and then substantially elevates NO in the bloodstream. That is a cleaner, more effective avenue of supporting circulation, blood pressure, and physical performance.
The Underlying Support Dynamics:
• Vitamin B12: Required for energy metabolism and nerve health. A common deficiency among those above fifty could lead to fatigue and cognitive issues. B12 in CircO2 supports general energy production and aids in healthy nitric oxide synthesis.
• Vitamin C: A two-for-one antioxidant. It serves as a cofactor for the enzymes that are involved in NO production and helps preserve already formed nitric oxide molecules from oxidative stress (free radicals) and prolongs their effectiveness.
• Magnesium: The blood vessel relaxer. This essentially calms and relaxes the smooth muscles of blood vessels, complementing the vasodilation activity of NO, while also supporting healthy heart rhythm and muscle recovery and giving its cardiovascular benefits a final touch.
Together, these ingredients do not merely create nitric oxide; rather, they create the most optimal environment for it to flourish and exert its far-reaching beneficial effects across your entire body.
The Life-Changing Benefits of CircO2
Restoring your nitric oxide to more youthful levels has a ripple effect across nearly every aspect of your health and daily life. Users of CircO2 report a transformation that goes beyond a simple “energy boost.”
• Sustained Energy & Stamina: Experience an end to the afternoon crash. With improved oxygen delivery to muscles and tissues, your body operates more efficiently. You’ll find you have the endurance to power through your day, enjoy activities you love, travel, or play with grandkids without being sidelined by fatigue.
• Sharper Mind & Enhanced Memory: Your brain is a massive consumer of oxygen and nutrients. Better blood flow means better brain performance. Users notice clearer thinking, quicker recall (like remembering names and where you left your keys), and improved concentration, helping to turn frustrating “senior moments” into a thing of the past.
• Promotes Healthy Blood Pressure: Nitric Oxide is your body’s natural blood pressure regulator. By supporting flexible, relaxed arteries, CircO2 helps maintain blood pressure already within a normal range, often leading to more favorable readings that impress both you and your doctor.
• Improved Mobility & Joint Comfort: Poor circulation can starve joints of lubricating fluids and nutrients. Enhanced blood flow delivers these vital compounds, which can help reduce stiffness and discomfort, supporting greater mobility and independence.
• Revitalised Intimacy & Sexual Performance: Sexual response is heavily dependent on healthy blood flow. By supporting optimal circulation to all areas of the body, CircO2 can help enhance arousal, performance, and satisfaction for both men and women.
• Better Sleep & Morning Alertness: The body’s repair processes rely on good circulation during sleep. Furthermore, balanced NO levels support healthy circadian rhythms. Users often report falling asleep more easily, sleeping more soundly, and waking up feeling genuinely refreshed, not groggy.
• Warmer Hands and Feet: Say goodbye to constantly cold extremities. Improved circulation ensures warm, oxygen-rich blood reaches your fingers and toes, a simple yet profound indicator of better vascular health.
Try CircO2 Risk-Free with Our 90-Day Guarantee
We’re so confident CircO2 will transform how you feel, we offer a “Down to the Last Lozenge” guarantee.
If you’re not completely satisfied for any reason, simply return the box – even if it’s empty – within 90 days for a complete refund.
Choose the number of boxes you will order today. It’s entirely up to you, but we suggest you order at least 3 boxes. You’ll save $15. And we’ll cover the cost of shipping, too!
Since you can try CircO2 for almost 90 days, 100% RISK FREE, you have absolutely nothing to lose … and everything to gain!
Plus, once you feel the CircO2 difference, you’ll understand why people don’t ever want to run out.
Reviews Based on more than thousands of satisfied Customers!
Jake L.
Canada
December 2, 2025
Nitro oxide *
Gives the energy that one looses thorough out the day
I Recommend This Supplement Verified Customer
San Gabriel Q.
Bridgewater, NJ
November 28, 2025
I like and recommend this supplement *
CircO2 is my favorite supplement for my blood pressure. I used this supplement for many years now and I usually stock up for 5-7 months. I used this in place of my regular prescription drugs which I stop for several years now. I will continue using this supplement since it keeps my blood pressure in normal range.
I Recommend This Supplement Verified Customer
Linda S.
Sanford, NC
November 26, 2025
Very satisfied *
I take this every other day and can honestly say they are great for helping me regulate my BP.
I Recommend This Supplement Verified Customer
Paul W.
Humble, TX
November 14, 2025
Pain disappears with CircO2 **
Before I started taking CircO2 in 2023 I was having trouble sleeping at night because of pain in my hands and arms. After taking CircO2 my pain went away and now I can sleep with no pain.
I Recommend This Supplement Verified Customer
Gary W.
November 11, 2025
Shared with Many ***
I’ve used circO2 with great results, so much so, I ordered about 20 boxes. I delivered them to my sponsored family in Tacloban Philippines.
I Recommend This Supplement Verified Customer
Yu Hsin Chang C.
November 4, 2025
My parents love this product ****
My parents are both over 70 and they are both satisfied with this product, and always ask me to purchase it!
I Recommend This Supplement Verified Customer
How is CircO2 Different From Other Products on the Market?
The nitric oxide supplement market is crowded, but CircO2 stands apart for several scientific and practical reasons:
1. Delivery Method: Lozenges vs. Pills. This is the most critical difference. While others use capsules that go straight to the acidic stomach (where ingredients can degrade), CircO2 uses a fast-dissolving lozenge that utilizes the essential oral nitrate pathway proven by MIT. This is not a marketing gimmick; it’s a fundamental application of human physiology for superior results.
2. Superior Active Ingredient: L-Citrulline vs. L-Arginine. Many cheaper formulas rely on L-arginine, which studies show is poorly absorbed and hard for the aging body to convert. CircO2 uses the more advanced, stable, and effective precursor, L-citrulline.
3. A Complete System vs. a Single Ingredient: CircO2 isn’t just “beet powder in a lozenge.” It’s a synergistic blend that includes absorption enhancers (Hawthorn Berry) and essential co-factors (B12, C, Magnesium) that protect and magnify the nitric oxide benefits. It addresses the entire production and utilization process.
4. Clinically-Verified Speed & Efficacy: The claim of a “200% increase in NO in 20 minutes” is based on the clinical testing of the oral nitrate method it employs. Most competitors make vague claims without referencing specific, applicable research on their own formulation.
5. Formulated by an Expert: CircO2 was developed under the guidance of Dr. Greg Eckel, a seasoned Naturopathic Physician with over 23 years of clinical experience, not just in a corporate lab.
Packaging, Pricing & Ironclad Guarantee
CircO2 comes in discreet, well-designed boxes containing a supply of easy-to-take lozenges.
Pricing & Savings Options:
• 1 Box (Sample): $49.95. Perfect for trying the product risk-free.
• 3 Boxes (Most Popular): $44.95 per box. You save $15.00 total and get FREE shipping. Total: $134.85.
• 6 Boxes (Biggest Savings): $41.50 per box. You save $50.70 total and get FREE shipping. Total: $249.00.
The “Down to the Last Lozenge” 90-Day Guarantee: Advanced Bionutritionals stands behind CircO2 with one of the most confident guarantees you’ll find. If you are not completely satisfied for any reason, simply return the box—even if it’s empty—within 90 days of purchase for a full, no-questions-asked refund (less return shipping). This allows you to truly experience the long-term benefits without any financial risk.
Frequently Asked Questions (FAQ)
Q: Is CircO2 safe?
A: CircO2 is formulated with ingredients generally recognized as safe. However, if you have a medical condition, are pregnant or nursing, or are taking medication (especially for blood pressure), it is always recommended to consult with your healthcare provider before starting any new supplement.
Q: How long will it take for me to know it’s working?
A: Many users report feeling a difference, often in energy or a sense of warmth, within the first 20-30 minutes as nitric oxide levels rise. For cumulative benefits like sustained energy, better sleep, and improved blood pressure readings, consistent use over several weeks is recommended.
Q: I read that using antiseptic mouthwash and fluoride toothpaste stops nitric oxide production. Should I stop?
A: Some studies suggest that antibacterial mouthwash can kill the oral bacteria needed for the first step of NO production. It’s generally advised to avoid using mouthwash immediately before or after taking CircO2. Using toothpaste is fine, but consider spacing it out from your CircO2 dose by 30-60 minutes if possible.
Q: Do I need to take it twice a day?
A: The recommended dosage is on the product label. For many, one lozenge daily provides significant benefits. Some choose to take a second later in the day for an extra boost. Consistency is more important than frequency.
Q: Do I have to let the lozenge dissolve completely?
A: Yes, for optimal results. Letting it dissolve slowly on your tongue ensures maximum contact time with the oral bacteria to initiate the nitrate conversion process.
Q: Caffeine and energy drinks give me the shakes. Will that happen with CircO2?
A: CircO2 works fundamentally differently. It doesn’t stimulate your nervous system like caffeine. Instead, it enhances your body’s natural energy production at a cellular level by improving oxygen delivery. Users typically experience clean, jitter-free energy without crashes.
Q: Where can I get CircO2?
A: To ensure you receive the authentic product and are eligible for the 90-day money-back guarantee, CircO2 should be purchased directly from the official Advanced Bionutritionals website.
Ready to Feel the Difference?
You don’t have to accept declining energy, fuzzy thinking, and fading vitality as an inevitable part of getting older. The science is clear: replenishing your nitric oxide levels can fundamentally change how you feel every single day.
CircO2 offers a proven, efficient, and risk-free way to do just that. Backed by groundbreaking MIT research, formulated with precision, and protected by a 90-day guarantee that lets you test it in your own life, the only thing you have to lose is the fatigue and brain fog holding you back.
Choose your package today.
For the best value and to ensure you don’t run out, the 3-box or 6-box bundles with free shipping are the smart choice. Click the button below, place your order, and take the first step toward reclaiming your energy, your sharpness, and your zest for life. Your body—and your future self—will thank you.
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